934660-93-2

If you are going to consult the information about 934660-93-2 from one of the leading 934660-93-2 manufacturers and suppliers in China,Website:://.biopharmaleader.net, Biopharmaleader Co.,Ltd is always at your service.Product InformationCAS NO.934660-93-2 Product NameCobimetinibSynonymsXL518;GDC 0973FormulaC21H21F3IN3O2Molecular Weight531.31Spec / Purity98%minSupply CapacityDetailsCobimetinib (GDC-0973, XL-518) is a MEK inhibitor being . It is being studied in combination with BRAF inhibitors to treat several cancers. Early data showed that administration of Cobimetinib in combination with the BRAF inhibitor vemurafenib increased progression-free survival in melanoma patients with a BRAF V600 mutation by 3.7 months compared to vemurafenib alone. Phase 3 clinical trials are ongoing and expected to complete by 2017. After good results in 2014 the combination has been submitted to EC and FDA for marketing approval.